Positioning:
        
        
            The 2010 S-Class (W221) represented the pinnacle of Mercedes-Benz's luxury sedan offerings, competing directly with rivals like the BMW 7 Series, Audi A8, and Lexus LS.
        
     
    
    
        
            Key Competitors 2010:
        
        
            BMW 7 Series (F01/F02), Audi A8 (D3), Lexus LS (XF40), Porsche Panamera (970)
        
     
    
    
        
            Luxury And Technology:
        
        
            The W221 S-Class was renowned for its advanced technology, refined ride quality, opulent interior, and sophisticated safety features, setting benchmarks in the luxury segment.
        
     
    
    
        
            Accuracy And Completeness:
        
        
            This manual provides the exact, vehicle-specific information used by authorized Mercedes-Benz technicians, ensuring accuracy for diagnostics, maintenance, and repairs, far surpassing generic aftermarket guides.
        
     
 
    
    
    
        
            Models Covered:
        
        
            All 2010 Mercedes-Benz S-Class (W221) variants, including S350, S450, S550, S600, S63 AMG, S65 AMG
        
     
    
        
            Repair Scope:
        
        
            Comprehensive A-Z repair coverage for all vehicle systems
        
     
    
    
        
            Page Count:
        
        
            Estimated 3000+ pages (typical for full factory service manuals)
        
     
    
    
        
            Type:
        
        
            Factory Service and Repair Manual
        
     
    
    
    
    
 
    
    
    
        
            Powertrain:
        
        
            Engine mechanicals, fuel, ignition, exhaust, cooling, lubrication, engine management systems (ECU), automatic transmissions, drivetrain (RWD/4MATIC)
        
     
    
        
            Chassis:
        
        
            Suspension (Airmatic, ABC), steering, brakes (ABS, ESP, SBC), wheels, tires
        
     
    
        
            Body And Exterior:
        
        
            Body structure, panels, doors, hinges, locks, glass, mirrors, exterior trim, convertible top (if applicable)
        
     
    
        
            Interior:
        
        
            Seating systems, upholstery, dashboard, interior trim, climate control, comfort features, interior lighting
        
     
    
        
            Electrical:
        
        
            Battery, charging system, starting system, lighting (headlights, taillights, interior), wiring diagrams, fuses, relays, multiplex communication (CAN bus), instrument cluster, infotainment system, power accessories (windows, seats, sunroof)
        
     
    
        
            Comfort And Safety:
        
        
            Climate control (THERMATIC/THERMOTRONIC), seat heating/ventilation, active multi-contour seats, ambient lighting, airbags, seatbelt systems, park assist, adaptive cruise control (DISTRONIC PLUS)
        
     
    
    
        
            Maintenance:
        
        
            Scheduled maintenance intervals, fluid changes (oil, coolant, brake fluid, transmission fluid), filter replacements (oil, air, cabin, fuel), spark plug replacement, belt inspections/replacement
        
     
    
        
            Diagnostics And Troubleshooting:
        
        
            Diagnostic trouble codes (DTCs), symptom-based troubleshooting, electrical system diagnosis, component testing
        
     
    
        
            Repair And Replacement:
        
        
            Component removal and installation procedures for all major systems, including engine overhaul, transmission rebuild, suspension component replacement, brake system repair, electrical component replacement
        
     
    
        
            Specifications And Tolerances:
        
        
            Torque specifications, clearances, alignment data, fluid capacities, pressure specifications, electrical specifications
        
     
    
        
            Special Tools And Equipment:
        
        
            Identification and usage of specialized tools required for specific repair procedures
        
     
    
    
        
            Depth:
        
        
            In-depth, factory-level technical information suitable for professional technicians and advanced DIY enthusiasts. Covers all aspects from basic maintenance to complete vehicle overhauls.
        
     
 
    
        
            โ๏ธ Engine Specifications
        
     
    
    
        
            S450 Engine:
        
        
            4.7L V8 (M272/M273)
        
     
    
        
            S550 Engine:
        
        
            5.5L V8 (M273)
        
     
    
        
            S600 Engine:
        
        
            5.5L Twin-Turbo V12 (M275)
        
     
    
        
            S63 Amg Engine:
        
        
            6.2L V8 (M156)
        
     
    
        
            S65 Amg Engine:
        
        
            6.0L Twin-Turbo V12 (M275)
        
     
    
    
        
            S550 Horsepower:
        
        
            382 hp @ 6000 rpm
        
     
    
        
            S550 Torque:
        
        
            391 lb-ft @ 2800-4000 rpm
        
     
    
        
            S600 Horsepower:
        
        
            510 hp @ 5000 rpm
        
     
    
        
            S600 Torque:
        
        
            612 lb-ft @ 1800-3500 rpm
        
     
    
    
        
            Fuel Delivery:
        
        
            Electronic Fuel Injection (EFI), Sequential Multi-Port Fuel Injection (MPI)
        
     
    
        
            Recommended Fuel:
        
        
            Premium Unleaded (91 octane or higher recommended for most models)
        
     
 
    
    
    
        
            Length:
        
        
            Approx. 5,097 mm (199.1 in) for standard wheelbase, 5,225 mm (205.7 in) for long wheelbase
        
     
    
        
            Width:
        
        
            Approx. 1,872 mm (73.7 in)
        
     
    
        
            Height:
        
        
            Approx. 1,473 mm (58.0 in)
        
     
    
    
        
            Curb Weight:
        
        
            Varies by model, approx. 1,800 - 2,100 kg (3,968 - 4,630 lbs)
        
     
    
        
            Gross Vehicle Weight Rating:
        
        
            Varies by model, typically around 2,450 - 2,700 kg (5,400 - 5,950 lbs)
        
     
 
    
    
    
        
            NHTSA Rating:
        
        
            Generally achieved 5-star ratings in frontal and side crash tests where tested (specific model year ratings may vary).
        
     
    
        
            IIHS Rating:
        
        
            Typically awarded 'Top Safety Pick' status.
        
     
    
    
        
            Driver Assistance Suite:
        
        
            DISTRONIC PLUS (Adaptive Cruise Control), PRE-SAFEยฎ Brake, Lane Keeping Assist, Blind Spot Assist, PARKTRONIC, BAS PLUS (Brake Assist System Plus)
        
     
    
    
        
            Airbags:
        
        
            Front airbags, side airbags, window curtain airbags, pelvic airbags (front and rear), active head restraints
        
     
    
        
            Body Structure:
        
        
            High-strength steel passenger cell, crumple zones
        
     
 
    
    
    
        
            Command System:
        
        
            COMAND APS (Cockpit Management and Navigation) system with integrated navigation, radio, CD/DVD player, and Bluetooth connectivity. The 2010 refresh included an updated interface and hard drive-based navigation.
        
     
    
    
        
            Active Safety Features:
        
        
            Adaptive Cruise Control (DISTRONIC PLUS), Active Lane Keeping Assist, Active Blind Spot Assist, Night View Assist PLUS (optional)
        
     
    
    
        
            Bluetooth Integration:
        
        
            Standard Bluetooth hands-free calling and audio streaming capabilities.
        
     
    
    
        
            Keyless Go:
        
        
            Keyless ignition and access system (optional).
        
     
    
        
            Harman Kardon Audio:
        
        
            Optional high-fidelity Harman Kardon LOGIC 7 surround sound system.
        
     
 
    
    
    
        
            Oil Change Interval:
        
        
            Typically every 10,000 miles or 1 year, whichever comes first (varies by driving conditions and specific engine oil used, refer to manual for exact 'Service A' or 'Service B' schedules).
        
     
    
        
            Major Service Intervals:
        
        
            Brake fluid change every 2 years. Spark plugs typically every 60,000 - 100,000 miles depending on engine type. Transmission fluid and filter service typically around 40,000 - 60,000 miles (critical for 7G-TRONIC).
        
     
    
    
        
            Engine Oil Spec:
        
        
            MB 229.5 (e.g., Mobil 1 0W-40, Castrol Syntec 0W-30/5W-30). Consult manual for specific engine requirements.
        
     
    
        
            Coolant Spec:
        
        
            MB 325.0 or 326.0 (Glycol-based, blue color), typically a 50/50 mix with distilled water.
        
     
    
        
            Power Steering Fluid Spec:
        
        
            MB 343.0 or 001-989-24-03.
        
     
    
    
        
            Air Suspension Components:
        
        
            Airmatic or ABC suspension struts can leak or fail over time. Air compressor can also be a failure point.
        
     
    
        
            Transmission Mechatronics:
        
        
            The 7G-TRONIC transmission's mechatronic unit can develop electrical issues or premature wear, especially on earlier models if fluid changes are neglected.
        
     
    
        
            Ignition Coils:
        
        
            Misfires can occur due to failing ignition coils, particularly on V8 and V12 engines.
        
     
    
        
            Harmonic Balancer:
        
        
            The crankshaft harmonic balancer on certain V8 engines (M273) can degrade, leading to rattling noises and potential belt slippage.
        
     
    
        
            Camshaft Timing Phasers:
        
        
            Camshaft adjusters (phasers) on M272 V6 and M273 V8 engines can fail, leading to rough idling and check engine lights. The manual details diagnosis and replacement procedures.
        
     
 
    
        
            ๐ Awards & Recognition
        
     
    
    
        
            Previous Generation Awards:
        
        
            The S-Class lineage consistently receives accolades for luxury, safety, and innovation, often including 'Car of the Year' awards from automotive publications in previous generations.
        
     
    
        
            Safety Recognitions:
        
        
            Consistent recognition from IIHS and NHTSA for its advanced safety features and structural integrity.
        
     
    
    
        
            Luxury Segment Ranking:
        
        
            Consistently ranked among the top luxury sedans for ride comfort, build quality, and technological integration by automotive critics.